THE VAN DEN HOOGENHOF LAB
RNA splicing in cardiac disease
THE VAN DEN HOOGENHOF LAB
RNA splicing in cardiac disease
About the lab
The van den Hoogenhof lab is a newly formed Junior Research Group at the Innovation Campus Region Rhein Neckar. The group is embedded in the Institute of Experimental Cardiology, which is a highly innovative and well-equipped institute, and part of the Heidelberg University Hospital. The van den Hoogenhof lab studies RNA splicing processes as well as the functional effects of missplicing and splice variants in the heart.
Currently, the group focuses on 3 main topics;
1) the molecular mechanisms underlying RBM20 cardiomyopathy,
2) the role of minor splicing in the heart, and
3) the identification and characterization of novel (master) splicing regulators in the heart.
Dr. Maarten van den Hoogenhof has worked in renowned labs in the US, the Netherlands, and Germany, and recently started his own Junior Research Group.
The lab works closely together with labs around the world, including the lab of Prof. Johannes Backs (Heidelberg, Germany) and Prof. Lars Steinmetz (Stanford, USA/Heidelberg, Germany).